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KMID : 0545120140240010008
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Journal of Microbiology and Biotechnology
2014 Volume.24 No. 1 p.8 ~ p.12
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Biofilm Formation and Antibiotic Resistance in Salmonella Typhimurium Are Affected by Different Ribonucleases
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Margarida Saramago
Susana Domingues
Sandra Cristina Viegas
Cecilia Maria Arraiano
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Abstract
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Biofilm formation and antibiotic resistance are important determinants for bacterial pathogenicity. Ribonucleases control RNA degradation and there is increasing evidence that they have an important role in virulence mechanisms. In this report, we show that ribonucleases affect susceptibility against ribosome-targeting antibiotics and biofilm formation in Salmonella.
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KEYWORD
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Salmonella, biofilms, antibiotics, RNases, RNA
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